In a striking yet unsurprising paradox, Russia, whose propaganda relentlessly attacks the West, is
becoming increasingly dependent on Western-made antidepressants. Today, life in Russia offers no shortage of reasons for anxiety and depression, including, to name just a few, the ongoing war with Ukraine and
“hidden” mobilization,
political repression and a
sharp economic slowdown that has led to widespread job losses. Russian pharmacies
report rising sales of sertraline, fluoxetine and escitalopram (trade names: Zoloft, Prozac and Cipralex), so-called selective serotonin reuptake inhibitors (SSRIs). It was precisely this class of antidepressants that, nearly three decades ago, broke into Western markets and became a routine part of the everyday lives of millions of Americans.
It all began in the late 1950s, when the first antidepressant medications were developed almost simultaneously in the
US and
Europe. Both proved effective in treating chronically and severely depressed patients. However, these drugs came with
significant side effects and carried serious risks in case of overdose. In the late 1980s, a new antidepressant called Prozac
entered the US market and then quickly spread worldwide. It was an
SSRI, which, compared with earlier antidepressants, was believed to treat depression and anxiety more effectively while causing far
fewer side effects. Prozac was touted as a “wonder drug” that not only cured clinically depressed patients but also helped people
who had no clinical depression to become more active, energetic, positive and even successful in their careers.
As the drug became wildly popular, many began to debate not only its effects on the health of users but also its broader cultural and social implications. For example, New York-based psychiatrist Peter Kramer controversially argued in his book
Listening to Prozac that the drug could reshape personality itself, while writer Elizabeth Wurtzel, who was taking antidepressants herself, wrote the bestselling memoir
Prozac Nation about her experience with depression. Her book further embedded Prozac in the American cultural imagination and even inspired a
film adaptation. Some media outlets suggested that a full-fledged “
Prozac culture” had emerged in the US. Prozac’s success paved the way for other SSRIs (among them is
Zoloft, currently popular in Russia), which were soon approved and made available.
Today, after more than 35 years of widespread antidepressant use, Americans are increasingly questioning the
safety and
efficacy of SSRIs, drawing attention to their
side effects. Many discussions also focus on how these drugs may disrupt a
person’s sense of identity with some users uncertain about who they are without medication. This is taking place as countries like Russia have recently begun to embrace antidepressants on a mass scale.
Soviet psychiatrists
framed depression as a short-term response to a set of purely personal problems, which could be helped with talk therapy and sedatives. When the USSR collapsed, Russia found itself in the throes of a series of
profound economic and social crises and shocks. For many it was too much to take. In the mid-1990s, newspapers began to report on widespread depression in the country, encouraging readers to seek psychiatric help and
even SSRIs, discussing them as a possible way to keep one’s sanity. Yet many Russians remained
wary of psychiatrists and suspicious of Western antidepressants. Throughout the 2000s, even though celebrity psychiatrists such as
Dr Kurpatov continued to raise public awareness of antidepressants in their books, these medications remained relatively uncommon.